Almac Discovery

Almac Discovery is a research driven drug discovery company dedicated to the development of novel and innovative approaches to the treatment of diseases of unmet need (including oncology and CNS), by applying a target class approach. The Almac Discovery business model is to develop preclinical stage assets which are then licenced to pharmaceutical or biotech partners for further development. We also look to collaborate with partners to apply our medicinal chemistry and translational biology expertise to targets of mutual interest. Key research themes include deubiquitinase enzymes and protein drug conjugates.

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Almac Group

The Almac Group is an established contract development and manufacturing organisation that provides the most unique range of integrated drug development services available to the pharmaceutical & biotech industry.

We are a privately owned organisation that has organically grown over 50 years and now employs in excess of 5,000 high skilled personnel. Almac is headquartered in Craigavon, Northern Ireland with 17 global facilities across Europe, USA and Asia.

Our quality, innovation and efficiency are testament to the fact that over 600 companies worldwide trust Almac for their Chemical, Pharmaceutical and Clinical Development needs.

Addressing the increasing pressure for Biopharma companies to bring their clinical candidates through their pipeline faster, more efficiently and at a lower cost, Almac provides an integrated CMC service, bridging the gap between drug substance and drug product development.

As an established provider of both drug substance (advanced intermediates and Active Pharmaceutical Ingredients – small molecules and peptides) and drug product development services, and by offering these within an integrated package, our client partners are assured of scientific continuity from a dedicated project team, resulting in significant savings in both time and costs.

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ARCINOVA

Arcinova is an agile Contract Development & Manufacturing Organisation (CDMO), providing the pharmaceutical industry with a full suite of drug substance, drug product and analytical support services from preclinical through to small scale commercial.

From our world-class 15,000m2 facility (ex-Sanofi, Covance), we offer process, research, development, scale-up and small scale manufacturing, including bioanalysis, regulatory and consulting services. We also have niche expertise in radiolabelling, providing 14C radiolabelled material for non-clinical and clinical needs.

Our large company track record and compliance coupled with the responsiveness and agility of a smaller company allows us to deliver high quality end-to-end solutions in a timely and cost-effective manner.

Our mission at Arcinova is to deliver best-in-class technology services in the fields of contract research, development and small scale manufacturing whilst minimising risk and overall cost.

Shift Bioscience Ltd

Shift Bioscience is a biotech startup targeting the root causes of aging to extend healthy lifespan

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Silence Therapeutics plc

Silence Therapeutics develops a new generation of medicines by harnessing the body’s natural mechanism of RNA interference, or RNAi, within its cells.

Our proprietary technology can selectively inhibit any gene in the genome, specifically silencing the production of disease-causing proteins. Using our enabling delivery systems, we have achieved an additional level of specificity by delivering our therapeutic RNA molecules exclusively to target cells. Silence’s proprietary RNA chemistries and delivery systems are designed to improve the stability of our molecules and enhance effective delivery to target cells, providing a powerful modular technology well suited to tackle life-threatening diseases.

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