Eurofins Selcia

Selcia, now part of Eurofins, is a global leader in 14C custom radiolabelling, stable isotope labelling and analytical services. With many years of experience our team of expert synthetic radiochemists can prepare radiolabelled molecules of almost any complexity for use in regulatory studies by the life sciences and chemical industries to understand: preclinical and clinical drug metabolism, human mass balance (GMP 14C Radiolabelled API), dermal penetration, tissue distribution and environmental fate. Selcia also offers GLP NMR and analytical problem solving services to support regulatory submissions, as well as the profiling and synthesis of metabolites and process impurities.  www.selcia.com 

 

  • 14C Custom Radiolabelling for pre-clinical studies (ADME, Dermal Penetration, E-fate)  
  • GMP Radiolabelled API for Clinical Trials , 14C-API for hAME and mass balance  
  • Stable Labelling  (13C, 2H, 15N) Internal Standards, Metabolites and Impurities  
  • GLP Analysis Certification and Problem Solving including GLP NMR 

 

Radiolabelling to support Life Sciences: • Metabolism • Distribution • Mass Balance • Micro-dosing • Environmental fate • Dermal Penetration 

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Twitter Account
@SelciaLtd

Evgen Pharma

Evgen is a clinical stage drug development company focussed on the development of sulforaphane-based compounds, a new class of pharmaceuticals which are synthesised in a proprietary, well-tolerated, stable formulation. 

There is a comprehensive intellectual property package over this technology, covering novel compositions and manufacturing methods. 

Evgen exploits sulforaphane’s activity in three distinct disease-relevant cellular pathways; inhibition of pSTAT3, of importance in controlling cancer metastases, up-regulation of Nrf2, a therapeutic target associated with a broad range of diseases which are characterised by excessive oxidative stress, and inflammation and inhibition of SHP2, a target that has relevance in a number of solid tumours and haematological cancers.

Twitter Account
@EvgenPharma

Fusion Antibodies

Established in 2001, Fusion Antibodies is a Collaborative Research Organisation (CRO) with its headquarters in Northern Ireland. We are world leaders in antibody development services specializing in the discovery, engineering and supply of pre-clinical biologics to clinical Cell Line Development.

We have guided hundreds of projects through critical pre-clinical stages, repeatedly proving our expertise as we strive to bring about a positive change in the healthcare industry.

Our approach to engineering and optimization is often to harness the power of the natural somatic hypermutation space. Fusion offers flexibility and agility while delivering clinical candidates focusing on developability, manufacturability and function.

Fusion has developed a number of unique, proprietary technology platforms. Our suite of development capabilities include:

  • Antibody humanization (CDRx™)
  • Affinity maturation (RAMP™)
  • Protein engineering
  • Discovery (mouse hybridoma and rabbit B cell approaches)
  • Protein production – CHO and other mammalian systems
  • Cell Line Development – cGMP ready mammalian cell lines (up to 8 g/L)
  • Expert scientific & technical advisory services
  • Bespoke & collaborative large-scale research and development programs
Twitter Account
@FsnAntibodies

hVIVO

We are hVIVO plc (formerly Open Orphan plc) a rapidly growing specialist contract research organisation (CRO) and the world leader in testing infectious and respiratory disease vaccines and antivirals using human challenge clinical trials. We provide end-to-end early clinical development services for our broad and long-standing client base of global biopharma companies.

The Group's fast-growing services business includes a unique portfolio of 10+ human challenge models to test a broad range of infectious and respiratory disease products, world class challenge agent manufacturing, specialist drug development and clinical consultancy services via its Venn Life Sciences brand, and a lab offering via its hLAB brand, which includes virology, immunology biomarker and molecular testing. The Group offers additional clinical field trial services such as patient recruitment and clinical trial site services.

hVIVO runs challenge studies in London from its Whitechapel quarantine clinic, its state-of-the-art QMB clinic with its highly specialised on-site virology and immunology laboratory, and its clinic in Plumbers Row. To recruit volunteers / patients for its studies, the Company leverages its unique clinical trial recruitment capacity via its FluCamp volunteer screening facilities in London and Manchester.

Twitter Account
@hVIVO_UK

IDEA Regulatory

IDEA is passionate about getting innovative products to patients with unmet needs and we particularly enjoy putting our full weight of innovative thinking and regulatory expertise behind innovative medicine.

Intract Pharma

Intract Pharma Limited is an oral drug delivery licensing and product development company offering a range of proprietary formulation technologies to deliver novel and optimised therapeutics targeted to patient needs. The company is a spin-out of University College London, and is centred around over 15 years of research and innovation from the laboratory of Professor Abdul Basit. Intract's range of formulation technologies includes Phloral™ for colon targeted delivery, and ProRelease™, a versatile microparticulate delivery system.

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@intractpharma

Isogenica

Isogenica is at the forefront of synthetic biology, pursuing a mission to provide the fastest, most efficient engine for therapeutic antibody discovery. Isogenica is developing LlamdA™ (single domain VHH) and Alexandria™ (human Fab) therapeutic antibodies based on its proprietary fully synthetic antibody libraries and leveraging its CIS Display and Colibra™ technologies to accelerate the discovery and development process.

Kuano

Our team combines drug discovery specialists with physicists, chemists and computer scientists committed to use cutting-edge technologies to make a difference to people’s lives.

Kuano's approach is to combine state-of-the-art simulation and AI to add quantum detail to structure based drug discovery. Our unique fusion of drug hunting and technology expertise allows us to illuminate new areas of chemical space enabling the design of next generation medicines.

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Libero Pharma

Providing patients with a new way to benefit from Naltrexone

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LifeArc

We transform promising life science ideas into medical breakthroughs that change patients’ lives.

Making life science life changing: We transform promising life science ideas into medical breakthroughs that change patients’ lives.

We specialise in early-stage translation – advancing lab-based scientific discoveries to a point at which they can be developed into the next generation of diagnostics, treatments and cures.

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@lifearc1